Student teams compete for best sepsis biosensor

Student teams compete for best sepsis biosensor
Student teams compete for best sepsis biosensor

In 2021, student teams were already busy. Then it was about research into the development of biosensors with which the flu virus in saliva can be measured quickly and easily. This time, the 14 student teams – from countries including Egypt, Canada, China, the Netherlands, Belgium and Germany – are working on innovative biosensors to detect the life-threatening inflammatory reaction sepsis more quickly.

Early diagnosis lowers risk of death

Naud van Rosmalen of the Eindhoven student team TEST explains the principle of the competition: “There are already biosensors that work on the basis of biomarkers on the market for sepsis. The challenge is to detect this serious inflammatory reaction faster, because the faster you can trace the disease, the better the patient’s chances of survival. Early diagnosis is essential because the chance of dying increases by ten percent every hour if not acted immediately. The aim of the competition is to stimulate the development of fast and advanced testing methods.”

Sepsis & facts

Worldwide, more than fifty million people develop sepsis every year. Sepsis is an acute inflammation that occurs all over the body in response to an infection in the blood. It is a life-threatening condition that puts millions of people in the ICU every year. Plus minus 35 percent of this group dies. Symptoms include fever, extreme pain, increased breathing, and increased heart rate. Using biosensors, this inflammatory response can be visualized, for the time being by detecting a certain concentration of the biomarker IL-6.

Biosensor Eindhoven University of Technology impresses

Each student team has its own method to detect that biomarker with a biosensor as quickly as possible. Some methods are somewhat similar, but the TU Eindhoven student team has a unique system that works with a laser. Bram Boerenkamp of the Eindhoven TEST team: “We aim this laser at a glass plate with blood plasma, whereby the label lights up more red at a higher concentration of IL-6.

What is special about our solution is that we expect that we will later be able to visualize several biomarkers regarding sepsis, because there are more of them that play a role in the condition. aIf you link these different biomarkers to differently colored labels, you can make them all visible with the same sample, and you have an unambiguous diagnosis even faster.” second prize in the category ‘Best business plan’ The winner in the main category was team LauSens from Sweden.

The article is in Dutch

Tags: Student teams compete sepsis biosensor

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