A clear cell meningioma is a tumor of the meninges. The meninges surround the brain and spinal cord.
This form of meningioma is called clear cell because this is what it looks like when a doctor views a piece of the tumor under a microscope. A meningioma is usually benign. Sometimes a benign meningioma still acquires malignant properties.
Someone may have a hereditary predisposition to clear cell meningioma. The cause of this predisposition is a change in a gene.
Someone with a clear cell meningioma may have characteristics such as:
- headache, sometimes someone feels nauseous and vomits
- cannot speak well
- double vision
- epileptic attacks
- pain in the back
- a strange feeling, such as tingling or loss of sensation, in those parts of the body that are under the tumor
In someone with a hereditary predisposition to this disease, the tumor is more often located in the membranes surrounding the spinal cord. It also occurs more often in children.
We do not know exactly how likely it is that someone with the hereditary predisposition will also develop clear cell meningioma. It differs between people at what age someone gets it and how sick someone then becomes. Probably not everyone with a hereditary predisposition will develop a clear cell meningioma.
Someone may also have a hereditary predisposition to meningioma due to another disease. For example, due to neurofibromatosis type 2, MEN-1, Li-Fraumeni syndrome or PTEN-harmatoma tumor syndrome.
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